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Histochemical detection of xanthine oxidoreductase activity in endothelial, epithelial and connective tissue cells in rat

✍ Scribed by Arnold Kooij; Klazina S. Bosch; Wilma M. Frederiks; Cornelis J.F. van Noorden


Book ID
113384841
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
122 KB
Volume
9
Category
Article
ISSN
0891-5849

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## Abstract PD98059 and U0126 are organic compound inhibitors frequently used to block the activity of the MEK‐1/2 protein kinase. In the present work, promoter activation analyses of xanthine oxidoreductase (XOR) in epithelial cells uncovered the unexpected opposite effect of these inhibitors on a