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Histamine stimulates glycogenolysis in human astrocytoma cells by increasing intracellular free calcium

✍ Scribed by Silvia Medrano; Eric Gruenstein; Ruth V.W. Dimlich


Book ID
115803495
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
577 KB
Volume
592
Category
Article
ISSN
0006-8993

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Variations in intracellular free calcium concentration (A1Cazfli) were measured in intact and isolated human astrocytoma cells (U373 MG) loaded with fura-2 acetoxymethylester. Microperfusion of 50 nM substance P (SP), applied for 1 s, increased [Ca" ' Ii by 351 nM from a stable basal level of [Ca2+l