Histamine modulates cellular events involved in tumour invasiveness in pancreatic carcinoma cells

Laminin-5 and modulation of keratin cyto

Laminin-5 and modulation of keratin cytoskeleton arrangement in FG pancreatic carcinoma cells: Involvement of IFAP300 and evidence that laminin-5/cell interactions correlate with a dephosphorylation of α6A integrin

✍ Baker, Scott E. ;Skalli, Omar ;Goldman, Robert D. ;Jones, Jonathan C.R. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 625 KB

Under normal culture conditions, epithelial cells of the FG line, derived from a pancreatic tumor, characteristically grow in mounds and fail to flatten efficiently onto their substrate. In such cells, keratin intermediate filaments (IFs) are concentrated in the perinuclear region. Furthermore, the