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Hippocampal mossy fiber sprouting is not impaired in brain-derived neurotrophic factor-deficient mice

✍ Scribed by R. Bender; B. Heimrich; M. Meyer; M. Frotscher

Publisher
Springer-Verlag
Year
1998
Tongue
English
Weight
359 KB
Volume
120
Category
Article
ISSN
0014-4819

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## Abstract Excess neuronal activity upregulates the expression of two neurotrophins, nerve growth factor (NGF) and brain‐derived neurotrophic factor (BDNF) in adult hippocampus. Nerve growth factor has been shown to contribute the induction of aberrant hippocampal mossy fiber sprouting in the inne