## Abstract Behavioral, lesion and neuroimaging evidence show striking commonalities between remembering past events and imagining future events. In a recent eventβrelated fMRI study, we instructed participants to construct a past or future event in response to a cue. Once an event was in mind, par
Hippocampal contributions to the episodic simulation of specific and general future events
β Scribed by Donna Rose Addis; Theresa Cheng; Reece P. Roberts; Daniel L. Schacter
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 181 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1050-9631
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Recent studies have demonstrated that remembering past experiences and imagining future scenarios recruits a core network including the hippocampus. Even so, constructing future events engages the hippocampus more than remembering past events. This fMRI study examined whether increased hippocampal activity for future events includes both specific and general events. Participants constructed specific and general past and future events during fMRI scanning. We replicated previous findings of increased activity in the right anterior hippocampus when constructing future relative to past events, and when constructing specific relative to general events. Importantly, both effects were driven by a significant interaction between temporal direction and specificity, with specific future events resulting in more activity than other conditions, including general future events. No regions exhibited greater activity during the construction of past relative to future events, or general relative to specific events. These results suggest that the process of constructing a detailed representation of a novel and specific future event differentially engages the right anterior hippocampus compared with other forms of event simulation and recall. Future work is needed to disambiguate the role of encoding, novelty and detail recombination in engaging the right anterior hippocampus during simulation. Β© 2010 WileyβLiss, Inc.
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