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Hippocampal cell genesis does not correlate with spatial learning ability in aged rats

โœ Scribed by David A. Merrill; Rajiv Karim; Michael Darraq; Andrea A. Chiba; Mark H. Tuszynski


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
322 KB
Volume
459
Category
Article
ISSN
0021-9967

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The effects of aging on extracellular glutamate and tissue dynorphin content in the hippocampus were examined in Fischer-344 rats. Young adult (4-month-old) and aged (24-month-old) rats were trained to find a hidden platform in the Morris water task. Aged rats were unable to acquire the spatial lear