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Highly Substituted Indole Library Synthesis by Palladium-Catalyzed Coupling Reactions in Solution and on a Solid Support

โœ Scribed by Worlikar, Shilpa A.; Neuenswander, Benjamin; Lushington, Gerald H.; Larock, Richard C.


Book ID
118194850
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
463 KB
Volume
11
Category
Article
ISSN
1520-4766

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## Abstract A simple and efficient procedure for the synthesis of 2โ€substituted benzo[__b__]furan derivatives has been developed by the reaction of 2โ€iodophenols and arylacetylenes in water catalyzed by palladium nanoparticles generated in situ in open air. The reaction does not require any additiv