## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
Highly Stereoselective Synthesis of Racemic Nonactic Acid and Synthesis of Dextrorotatory (2S,3S,6R,8R)-Nonactic Acid
✍ Scribed by Dr. Hans Zak; Prof. Dr. Ulrich Schmidt
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 228 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0044-8249
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## Abstract A new synthetic route to enantiopure (2__S__,4__R__)‐4‐hydroxypipecolic acid from commercial ethyl (3__S__)‐4‐chloro‐3‐hydroxybutanoate is reported. The synthesis is based on the Pd‐catalyzed methoxycarbonylation of a 4‐alkoxy‐substituted δ‐valerolactam‐derived vinyl triflate followed b
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
## Abstract Racemic, R‐ and S‐β‐hydroxybutyric acid were labelled with ^11^C in the carboxylic position by a two‐step stereospecific synthesis starting with carrier‐added [^11^C]cyanide and R/S, R‐ or S‐propylene oxide. Hydrolysis of the intermediate nitrile with hydrochloric acid gave racemic [1‐^