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Highly stereoselective synthesis of methynolide, the aglycone of the 12-membered ring macrolide methymycin, from D-glucose

✍ Scribed by Yuji Oikawa; Tatsuyoshi Tanaka; Osamu Yonemitsu

Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
281 KB
Volume
27
Category
Article
ISSN
0040-4039

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✦ Synopsis

A highly stereoselective and efficient synthesis of methynolide, the aglycone of 12membered macrolide methymycin, was achieved from of Cl-C8 and C9-Cl3 segments synthesized from D-glucose by employing some stereoselective reactions and benzyl-type protecting groups.

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