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Highly stereoselective synthesis of antitumor agents: both enantiomers of goniothales diol, altholactone, and isoaltholactone

โœ Scribed by Jhillu Singh Yadav; Atcha Krishnam Raju; Ponugoti Purushothama Rao; Gurram Rajaiah


Book ID
108283997
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
196 KB
Volume
16
Category
Article
ISSN
0957-4166

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A concise and stereoselective synthesis
โœ J.S. Yadav; G. Rajaiah; A.Krishnam Raju ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 236 KB

A concise and flexible stereoselective route to synthesize both enantiomers of the highly functionalized a,b-unsaturatedd-lactones, altholactone and isoaltholactone, from readily available cinnamyl alcohol is described. This approach derived its asymmetry from Sharpless catalytic asymmetric epoxidat