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Highly stereoselective approach to chiral building block possessing three contiguous asymmetric centers. Preparation of four possible diastereomers of β,β′-dimethyl-bis-homoallylic alcohol derivative

✍ Scribed by Keisuke Suzuki; Eiji Katayama; Katsuhiko Tomooka; Takashi Matsumoto; Gen-ichi Tsuchihashi


Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
247 KB
Volume
26
Category
Article
ISSN
0040-4039

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✦ Synopsis


AZZ four diastereomers of chiral alcohol 2 with three contiguous chiral centers were stereoselectiveZy prepared via diastere~selective addition of nucleophiles (crotyl metal or H-J to n-methyZ-B,y-unsaturated carbonyl compounds 1.