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Highly Stereoselective Aldol Reaction for the Synthesis of γ-Lactones Starting from Tartaric Acid

✍ Scribed by Barros, M. Teresa; Burke, Anthony J.; Lou, Ji-Dong; Maycock, Christopher D.; Wahnon, Jorge R.


Book ID
127321670
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
117 KB
Volume
69
Category
Article
ISSN
0022-3263

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A practical and enantiopure synthesis for the preparation of key intermediates of conformationally locked c-amino acid and nucleoside analogues is described. First, a highly stereoselective aziridine ring-opening reaction with phenylselenide anion was employed for the stereoselective synthesis of th