Highly sensitive spectrofluorimetric determination of trace amounts of prulifloxacin using the aluminium(III)–prulifloxacin system
✍ Scribed by Fengshan Yu; Weizhou Liu; Fang Chen; Ping Cai
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 251 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1522-7235
- DOI
- 10.1002/bio.1075
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✦ Synopsis
Abstract
The fluorescence of the prulifloxacin (PUFX)–Al(III) system was investigated . Experiments indicated that the fluorescence intensity of prulifloxacin could be greatly enhanced by Al(III) and sensitized by sodium dodecylbenzene sulphonate (SDBS). Accordingly, a sensitive spectrofluorimetric method for the determination of prulifloxacin was established. While excited at 275 nm, the enhanced fluorescence intensity at 412 nm of the system (Δ__F__) showed a good linear relationship with the concentration of prulifloxacin within the range 4.0 × 10^–8^–3.0 × 10^–6^ mol/L. The regression equation was Δ__F__ = 9.83 + 10.8 × 10^7^c (mol/L); the correlation coefficient and detection limit (3__σ__/k) were 0.99901 and 2.0 × 10^–8^ mol/L, respectively. The proposed method has been successfully applied to determine prulifloxacin in real pharmaceutical samples. The luminescence mechanism of the system is also discussed in detail. Copyright © 2008 John Wiley & Sons, Ltd.