Highly regioselective ring-opening of ฮฑ-
โ
Jun Hiratake; Kazuyoshi Yamamoto; Yukio Yamamoto; Jun'ichi Oda
๐
Article
๐
1989
๐
Elsevier Science
๐
French
โ 169 KB
Lipase Amano P irreversibly catalyzed a ring-opening of a-substituted cyclic acid anhydrides 1 preferentially at the less hindered carbonyl goup to give monoesters with high regioselectivity.