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Highly regioselective reduction of unsymmetrical cyclic carboxylic acid anhydrides to ?-lactones

โœ Scribed by Morand, Peter; Kayser, Margaret


Book ID
120241039
Publisher
The Royal Society of Chemistry
Year
1976
Tongue
English
Weight
107 KB
Volume
9
Category
Article
ISSN
0022-4936

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Highly regioselective ring-opening of ฮฑ-
โœ Jun Hiratake; Kazuyoshi Yamamoto; Yukio Yamamoto; Jun'ichi Oda ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 169 KB

Lipase Amano P irreversibly catalyzed a ring-opening of a-substituted cyclic acid anhydrides 1 preferentially at the less hindered carbonyl goup to give monoesters with high regioselectivity.