๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Highly pyrimethamine-resistant alleles of dihydrofolate reductase in isolates of Plasmodium falciparum from Tanzania

โœ Scribed by Michele D. Hastings; Sarah J. Bates; Eric A. Blackstone; Stephanie M. Monks; Theonest K. Mutabingwa; Carol Hopkins Sibley

Book ID
108368630
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
477 KB
Volume
96
Category
Article
ISSN
0035-9203

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Rapid selection of dhfr mutant allele in
Rapid selection of dhfr mutant allele in Plasmodium falciparum isolates after the introduction of sulfadoxine/pyrimethamine in combination with 4-aminoquinolines in Papua New Guinea
โœ Toshihiro Mita; Akira Kaneko; Ilomo Hwaihwanje; Takahiro Tsukahara; Nobuyuki Tak ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 152 KB

To overcome the declining efficacy of the 4-aminoquinolines in Papua New Guinea, sulfadoxine/pyrimethamine (SP) was combined with the 4-aminoquinolines as the first line treatment for falciparum malaria since 2000. To assess how this change had affected SP resistant gene polymorphisms, we determined

Prevalence of pfcrt point mutations and
Prevalence of pfcrt point mutations and level of chloroquine resistance in Plasmodium falciparum isolates from Africa
โœ Carlo Severini; Michela Menegon; Anna Rosa Sannella; Maria Grazia Paglia; Pasqua ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 133 KB

The development in Plasmodium falciparum of the resistance to chloroquine (CQ) constitutes a public health priority, due to its direct influence in childhood mortality. The molecular basis for CQ resistance (CQR) is still unclear but, recently, a new relevant gene, named pfcrt, with several point mu