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Highly potent and selective inhibition of bovine viral diarrhea virus replication by γ-carboline derivatives

✍ Scribed by Mohammed T.A. Salim; Yukinori Goto; Takayuki Hamasaki; Mika Okamoto; Hiroshi Aoyama; Yuichi Hashimoto; Simone Musiu; Jan Paeshuyse; Johan Neyts; Matheus Froeyen; Piet Herdewijn; Masanori Baba


Book ID
113458449
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
468 KB
Volume
88
Category
Article
ISSN
0166-3542

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Highly potent and selective inhibition o
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## Abstract The bicyclic furo[2,3‐__d__]pyrimidine nucleoside analogues represent an entirely new class of fused furopyrimidine derivatives with unprecedented selectivity for varicella‐zoster virus (VZV). From extensive structure‐activity relationship (SAR) studies, the 6‐(__p__‐alkylphenyl)substit