Methodoloy for the polyene and related a
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Stephen Hanessian; Soumya P. Sahoo; Maurizio Botta
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Article
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1987
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Elsevier Science
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French
⚖ 231 KB
Structural units corresponding to the Clc-C2a and C32-C3B segments of amphotericin B were synthesized from a single chiral progenitor. In the previous paper,' we described an efficient and convergent synthesis of the Cl-Cl3 segment of amphotericin B2 starting with (S)-4-hydroxymethyl butyrolactone w