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Highly Enantioselective Synthesis of (E)-Allylic Alcohols.

✍ Scribed by Hsyueh-Liang Wu; Ping-Yu Wu; Biing-Jiun Uang


Publisher
John Wiley and Sons
Year
2007
Weight
28 KB
Volume
38
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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Enantioselective Synthesis of Deoxymanno
✍ Marie-CΓ©line Lamas; Max Malacria; Serge Thorimbert πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 278 KB πŸ‘ 1 views

## Abstract An efficient enantioselective synthesis of deoxymannojirimicin is reported. It is based on the unusual Sharpless asymmetric epoxidation of a silyl‐substituted allylic 1,4‐amino alcohol coupled with a further highly stereoselective intramolecular aldolization. Both enantiomers of deoxyma