Highly Enantioselective Ketone-Ene Reactions of Trifluoropyruvate: Significant Counterion Effect of the In(III)−PyBox Complex
✍ Scribed by Zhao, Jun-Feng; Tjan, Teguh-Budiono W.; Tan, Boon-Hong; Loh, Teck-Peng
- Book ID
- 127235993
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 286 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1523-7060
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📜 SIMILAR VOLUMES
A highly efficient enantioselective carbonyl-ene reaction of ethyl glyoxylate catalyzed by an In(III)-pybox complex, which is designed based on the counterion effect, is reported. Reactions of both aliphatic and aromatic 1,1-disubstituted olefins proceed smoothly to give enantioenriched homoallylic
## Abstract Most of the reactions carried out in a mixture of ionic liquid and DCE proceed faster than those carried out in pure DCE with comparable or better yields and enantioselectivities of the resulting tertiary homoallylic alcohols in shorter reaction times.