Highly Enantioselective Enone Epoxidation Catalyzed by Short Solid Phase-Bound Peptides: Dominant Role of Peptide Helicity †

Asymmetric enone epoxidation by short so

Asymmetric enone epoxidation by short solid-phase bound peptides: Further evidence for catalyst helicity and catalytic activity of individual peptide strands

✍ Albrecht Berkessel; Burkhard Koch; Claudio Toniolo; Mario Rainaldi; Quirinus B. 📂 Article 📅 2006 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 426 KB

## Abstract In the presence of short solid‐phase bound peptide catalysts, the Juliá–Colonna epoxidation of enones (such as chalcone) with hydrogen peroxide can be performed with high enantiomeric excess (≥95% ee). It was proposed earlier (A. Berkessel, N. Gasch, K. Glaubitz, C. Koch, __Organic Lett