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Highly Enantioselective Conjugate Addition of Dialkylzinc Reagents to Acyclic Nitroalkenes: A Catalytic Route to β 2 -Amino Acids, Aldehydes, and Alcohols

✍ Scribed by Duursma, Ate; Minnaard, Adriaan J.; Feringa, Ben L.


Book ID
124075945
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
65 KB
Volume
125
Category
Article
ISSN
0002-7863

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Enantioselective Catalytic Addition of F
✍ Dr. Walter Brieden; Roswitha Ostwald; Prof. Dr. Paul Knochel 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 407 KB 👁 1 views

To nBuLi (2.9 g. 46 mmol), constantly stirred at -8O"C, precooled pentane was added dropwise until a homogeneous solution was obtained (ca. 20 mL). After one week at -90 "C colorless blocks crystallized with a melting point of -34(2) 'C. rBuLi: tBuLi (2.2 g, 34 mmol) was treated as described for nBu