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Highly Enantioselective and Regioselective Biocatalytic Azidolysis of Aromatic Epoxides

✍ Scribed by Lutje Spelberg, Jeffrey H.; van Hylckama Vlieg, Johan E. T.; Tang, Lixia; Janssen, Dick B.; Kellogg, Richard M.

Book ID: 127311012
Publisher: American Chemical Society
Year: 2001
Tongue: English
Weight: 39 KB
Volume: 3
Category: Article
ISSN: 1523-7060
DOI: 10.1021/ol0067540

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## Abstract Azidolysis of epoxides followed by reduction of the intermediate azido alcohols constitutes a valuable synthetic tool for the construction of β‐amino alcohols, an important chemical functionality occurring in many biologically active compounds of natural origin. However, depending on co