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Highly Enantioselective Ag(I)-Catalyzed [3 + 2] Cycloaddition of Azomethine Ylides

✍ Scribed by Longmire, James M.; Wang, Bin; Zhang, Xumu


Book ID
111902948
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
54 KB
Volume
124
Category
Article
ISSN
0002-7863

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A silver(I)/ThioClickFerrophos complex catalyzed the endo selective asymmetric 1,3-dipolar cycloaddition reaction of methyl N-benzylideneglycinate (the source of azomethine ylides) with a,b-unsaturated esters and maleimides to give the endo-2,4,5-and 2,3,4,5-substituted pyrrolidines in good yields w