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Highly Enantioselective Addition of Trimethylsilylacetylene to Aldehydes Catalyzed by a Zinc–Amino-Alcohol Complex

✍ Scribed by Zhi-Yuan Li; Dr. Min Wang; Dr. Qing-Hua Bian; Bing Zheng; Jian-You Mao; Shuo-Ning Li; Dr. Shang-Zhong Liu; Dr. Ming-An Wang; Dr. Jiang-Chun Zhong; Dr. Hong-Chao Guo


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
237 KB
Volume
17
Category
Article
ISSN
0947-6539

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✍ Zhaoqing Xu; Rui Wang; Jiangke Xu; Chao-shan Da; Wen-jin Yan; Chao Chen 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 89 KB 👁 2 views

The enantioselective formation of C À C bonds is an area of intense research. [1,2] The asymmetric addition of alkynyl reagents to aldehydes is very useful for the synthesis of chiral secondary propargyl alcohols, which are important building blocks for many chiral organic compounds. [3] Several stu