Highly Enantio- and Diastereoselective Organocatalytic Asymmetric Domino Michael—Aldol Reaction of β-Ketoesters and α,β-Unsaturated Ketones.
✍ Scribed by Nis Halland; Pompiliu S. Aburel; Karl Anker Joergensen
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 183 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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## Abstract A chiral imidazolidine catalyst was shown to catalyze the highly enantio‐ and diastereoselective domino Michael‐aldol reaction of β‐diketone and β‐ketosulfone derivatives with α,β‐unsaturated ketones to form optically active cyclohexanones having three or four contiguous chiral centers.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v