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Highly efficient synthesis of steroid-17-spiro-5'-oxazolidine-2', 4' -diones from 17-keto steroids

โœ Scribed by Mauro Ginanneschi; Mario Chelli; Annamaria Papini; Gianfranco Rapi

Book ID
116065519
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
758 KB
Volume
55
Category
Article
ISSN
0039-128X

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๐Ÿ“œ SIMILAR VOLUMES

An Efficient Synthesis of 11ฮฒ-(4-Aminoph
An Efficient Synthesis of 11ฮฒ-(4-Aminophenyl)spiro[estr-4-ene-17ฮฒ,2โ€ฒ(5โ€ฒH)-furan]-3,5โ€ฒ-dione
โœ Jens Geisler; Arwed Cleve; Michael Harre ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 94 KB

AbstractรAn efยฎcient synthesis has been developed affording 11b-(4-aminophenyl)spiro[estr-4-ene-17b,2 H (5 H H)-furan]-3,5 H -dione (2), main metabolite of antiprogestin (Z)-11b-[4-(dimethylamino)phenyl]-17b-hydroxy-17a-(3-hydroxyprop-1-enyl)estr-4-en-3-one (1), in an overall yield of 21%.