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Highly efficient synthesis of peptides by rational utilization of novel coupling reagents

โœ Scribed by Li Peng; Xu Jie-Cheng


Book ID
102803638
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
728 KB
Volume
18
Category
Article
ISSN
0256-7660

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Efficient synthesis of highly functional
โœ Izzat T. Raheem; John D. Schreier; Michael J. Breslin ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 834 KB

We report the development of a novel three-component coupling reaction (3CC) for the synthesis of alkoxy tetrahydropyridopyrimidines. Systematic optimization of reaction parameters identified 3CC conditions tolerant of a wide array of functionality at all three sites of diversity, providing densely