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Highly efficient synthesis of buflavine: a unique Amaryllidaceae alkaloid

✍ Scribed by Poolsak Sahakitpichan; Somsak Ruchirawat

Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 132 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(03)01207-3

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✦ Synopsis

The Amaryllidaceae alkaloid buflavine 1 has been synthesized in three steps by Suzuki-Miyaura cross coupling, reduction and the cascade reactions of Pictet-Spengler type and Eschweiler-Clarke N-methylation.

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