𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection

✍ Scribed by Peters, Brock A; Kan, Zhengyan; Sebisanovic, Dragan; Pujara, Kanan; Wang, Zhiyong; Hong, Peter; Chow, Bernard; Stinson, Jeremy; Carlton, Victoria E H; Pham, Thinh Q


Book ID
109936601
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
267 KB
Volume
4
Category
Article
ISSN
1552-4450

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Rapid identification of somatic mutation
✍ Steven Bentivegna; Jianbiao Zheng; Eugeni Namsaraev; Victoria E.H. Carlton; Adam πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 367 KB

## Communicated by Richard Wooster Mismatch repair detection (MRD) was used to screen 93 matched tumor-normal sample pairs and 22 cell lines for somatic mutations in 30 cancer relevant genes. Using a starting amount of only 150 ng of genomic DNA, we screened 102 kb of sequence for somatic mutations