Rapid identification of somatic mutation
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Steven Bentivegna; Jianbiao Zheng; Eugeni Namsaraev; Victoria E.H. Carlton; Adam
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Article
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2008
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John Wiley and Sons
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English
β 367 KB
## Communicated by Richard Wooster Mismatch repair detection (MRD) was used to screen 93 matched tumor-normal sample pairs and 22 cell lines for somatic mutations in 30 cancer relevant genes. Using a starting amount of only 150 ng of genomic DNA, we screened 102 kb of sequence for somatic mutations