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Highly efficient production of anti-HER2 scFv antibody variant for targeting breast cancer cells

✍ Scribed by Silvia Sommaruga; Alessio Lombardi; Agnese Salvadè; Serena Mazzucchelli; Fabio Corsi; Patrizia Galeffi; Paolo Tortora; Davide Prosperi


Book ID
105953327
Publisher
Springer
Year
2011
Tongue
English
Weight
435 KB
Volume
91
Category
Article
ISSN
1432-0614

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✍ Jeanett Fischgräbe; Martin Götte; Katharina Michels; Ludwig Kiesel; Pia Wülfing 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 600 KB

Human epidermal growth factor receptor 2 (HER2) is frequently overexpressed in human breast cancers. It is known to drive tumor growth and progression and represents a prominent target in breast cancer therapy. The endothelin (ET) system, in particular ET-1 and its receptor ET A R, is of major relev