Highly Efficient Cyanosilylation of Sterically Bulky Ketones Catalyzed by Tin Ion-Exchanged Montmorillonite

✍ Scribed by Jiacheng Wang; Yoichi Masui; Kenya Watanabe; Makoto Onaka

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 195 KB
• Volume: 351
• Category: Article
• ISSN: 1615-4150
• DOI: 10.1002/adsc.200800673

✦ Synopsis

Abstract

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Tin ion‐exchanged montmorillonite (Sn‐Mont) was found to be a powerful catalyst for the cyanosilylation of aromatic and aliphatic ketones having a carbonyl group in sterically congested circumstances with cyanotrimethylsilane, giving the corresponding cyanohydrin trimethylsilyl ethers in excellent yields.