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Highly Efficient and Facile Synthesis of 5-Azido-2′-Deoxyuridine

✍ Scribed by Gourdain, Stéphanie; Petermann, Christian; Harakat, Dominique; Clivio, Pascale


Book ID
120309001
Publisher
Taylor and Francis Group
Year
2010
Tongue
English
Weight
190 KB
Volume
29
Category
Article
ISSN
0732-8311

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ChemInform Abstract: Synthesis and Biolo
✍ S. H. KANG; A. K. SINHABABU; M. J. CHO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

Synthesis and Biological Activity of Bis(pivaloyloxymethyl) Ester of 2'-Azido-2'-deoxyuridine 5'-Monophosphate. -The title compound (III) which is the membrane-permeable prodrug of the phosphate (I), is evaluated with positive results for inhibition of cell growth with 60 tumor cell lines.