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Highly Efficient Alkylation to Ketones and Aldimines with Grignard Reagents Catalyzed by Zinc(II) Chloride.

โœ Scribed by Manabu Hatano; Shinji Suzuki; Kazuaki Ishihara


Publisher
John Wiley and Sons
Year
2006
Weight
30 KB
Volume
37
Category
Article
ISSN
0931-7597

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Highly Stereoselective and Efficient Add
โœ Giuseppe Bartoli; Marcella Bosco; Emanuela Di Martino; Enrico Marcantoni; Letizi ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 342 KB ๐Ÿ‘ 1 views

A highly efficient and stereoselective technique for additions to syn-ฮฒ-alkyl-ฮฒ-hydroxy-ฮฑ-methyl ketones is now available. The methodology is based on the conversion of the starting material into a trichlorotitanium alkoxide derivative, which is able to assume a stable cyclic arrangement exhibiting