Highly Stereoselective and Efficient Add
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Giuseppe Bartoli; Marcella Bosco; Emanuela Di Martino; Enrico Marcantoni; Letizi
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Article
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2001
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John Wiley and Sons
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English
โ 342 KB
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A highly efficient and stereoselective technique for additions to syn-ฮฒ-alkyl-ฮฒ-hydroxy-ฮฑ-methyl ketones is now available. The methodology is based on the conversion of the starting material into a trichlorotitanium alkoxide derivative, which is able to assume a stable cyclic arrangement exhibiting