𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Highly diastereoselective synthesis of 1,2-epoxy-4-hydroxyalkyl carbamates. Masked and activated α,γ-dihydroxy-alkanals and -alkanones

✍ Scribed by Dieter Hoppe; Jörg Lüßmann; Peter G. Jones; Dieter Schmidt; George M. Sheldrick


Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
232 KB
Volume
27
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Diastereoselective synthesis of 2,3,4-tr
✍ Jörg Lüßmann; Dieter Hoppe; Peter G. Jones; Christa Fittschen; George M. Sheldri 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 227 KB

The acid-catalyzed ring opening of the title epoxide 1 takes place at the C-l atom with retention of configuration at C-2 to form 2,3-cis-2-hydroxy-substituted y-lactol deriva= tives 3 In basic media, nucleophiles attack the C-Atom with inversion of configuration yielding 2,3-trans-lactols 5. Oxidat