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Highly Diastereoselective Nitrone Cycloaddition onto a Chiral Ketene Equivalent: Asymmetric Synthesis of Cispentacin

✍ Scribed by Aggarwal, Varinder K.; Roseblade, Stephen J.; Barrell, Juliet K.; Alexander, Rikki


Book ID
126116778
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
44 KB
Volume
4
Category
Article
ISSN
1523-7060

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For the purpose of practical preparations of a variety of enantiomerically pure uncommon Β’x-amino acids, alkylations of the chiral glycine equivalent 5, which possesses axially chiral binaphthol as an auxiliary, with several electrophiles were investigated. The alkylation proceeded smoothly in satis