Synthesis of 6-substituted tetrahydropyr
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Shang-Shing P. Chou; Hao-Chieh Chiu; Chia-Cheng Hung
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Article
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2003
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Elsevier Science
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French
β 170 KB
3-Sulfolenes 1 with various substituents at C-2 underwent [4+2] cycloaddition reactions with p-toluenesulfonyl isocyanate to give the teterahydropyridinones 4. Through N-detosylation and Hg(II)-mediated electrophilic addition/intramolecular cyclization of 4e and 4f, the indolizidine and quinolizidin