Highly chemo-, regio-, and stereoselective introduction of a cis-double bond into a thia-analogue of stearic acid

✍ Scribed by Peter H. Buist; H.Garry Dallmann; Robert T. Rymerson; Peter M. Seigel

• Book ID: 104233410
• Publisher: Elsevier Science
• Year: 1987
• Tongue: French
• Weight: 210 KB
• Volume: 28
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)81007-8

✦ Synopsis

Replacement of a methylene grouo by a sulfur atom at the 5-position of stearic acid does not prevent the introduction of a cis-double bond at the 9-,lO-positions.

previous communication', we showed that an enzymatic methylating system was able to unactivated double bond in the presence of a more nucleophilic thioether linkage only two carbons removed.