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Highly Acetylated Lanostane-Type Triterpenoids from Coprinus cinereus 120

✍ Scribed by Yuan-Zhen Liu; Yao-Yao Li; Yi-Fei Sun; Zhong-Hui Zheng; Si-Yang Song; Wen-Jin Su; Yue-Mao Shen


Publisher
John Wiley and Sons
Year
2012
Tongue
German
Weight
148 KB
Volume
95
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Two new highly acetylated lanostane‐type triterpenoids, coprinacin A (1) and coprinacin B (2), were isolated from the basidiomycetous strain Coprinus cinereus 120. The chemical structures of 1 and 2 were elucidated by spectroscopic analyses, including 1D‐ and 2D‐NMR experiments and FT‐ICR‐MS, and their in vitro cytotoxic activities against the human‐tumor cell line HeLa were established as modest.