High-yield expression and purification of p18 form of Bax as an MBP-fusion protein
β Scribed by Roman Eliseev; Andrey Alexandrov; Thomas Gunter
- Book ID
- 116827810
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 262 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1046-5928
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## Abstract Therapeutic proteins like human interferon Ξ±2 generally possess short serum halfβlives due to their small size, hence rapid renal clearance, and susceptibility to serum proteases. Chemical derivatization, such as addition of polyethylene glycol (PEG) groups overcomes both problems, but