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High-throughput x-ray crystallography for structure-based drug design

โœ Scribed by Kenneth E. Goodwill; Michael G. Tennant; Raymond C. Stevens

Book ID
114383436
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
73 KB
Volume
6
Category
Article
ISSN
1359-6446

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Over the past 12 years, drugs have been developed using structure-based drug design relying upon traditional crystallographic methods. Established successes, such as the drugs designed against HIV-1 protease and neuraminidase, demonstrate the utility of a structure-based approach in the drug-discove