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High throughput on-bead monitoring of solid phase reactions by Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS)

✍ Scribed by Tin Yau Chan; Ru Chen; Michael J. Sofia; Brian C. Smith; Dennis Glennon


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
217 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis


Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS) provides a method for high throughput on-bead monitoring of solid phase reactions. DRIFTS spectra can be acquired with a few milligrams of resin sample and sample preparation is not required.

Analysis time is short and an automated DRIFTS accessory is commercially available.