High throughput DNA sequence variant detection by conformation sensitive capillary electrophoresis and automated peak comparison
โ Scribed by Helen Davies; Ed Dicks; Philip Stephens; Charles Cox; Jon Teague; Chris Greenman; Graham Bignell; Sarah O'Meara; Sarah Edkins; Adrian Parker; Claire Stevens; Andrew Menzies; Matt Blow; Bill Bottomley; Mark Dronsfield; P. Andrew Futreal; Michael R. Stratton; Richard Wooster
- Book ID
- 116981503
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 215 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0888-7543
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Capillary array electrophoresis (CAE) is a novel technique, which allows for high throughput analysis of DNA fragments. When screening for mutations in whole populations or large patient groups it is necessary to have robust and well-characterized setups for high throughput analysis. For large-scale
Genetic diagnosis of an inherited disease or cancer often involves analysis for unknown point mutations in several genes; therefore, rapid and automated techniques that can process a large number of samples are needed. We describe a method for high-throughput single-strand conformation polymorphism