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High throughput comparative genomic hybridization array analysis of multifocal urothelial cancers

✍ Scribed by Hiroaki Kawanishi; Takeshi Takahashi; Masaaki Ito; Jun Watanabe; Shin Higashi; Toshiyuki Kamoto; Tomonori Habuchi; Tadashi Kadowaki; Gozoh Tsujimoto; Hiroyuki Nishiyama; Osamu Ogawa

Book ID: 108583696
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 650 KB
Volume: 97
Category: Article
ISSN: 1347-9032
DOI: 10.1111/j.1349-7006.2006.00259.x

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## Abstract Acute promyelocytic leukemia (APL) is typically associated with the t(15;17) that generates the __PML–RARA__ fusion protein. Animal models have shown that although the fusion protein is necessary, it is insufficient for the development of APL, implying that additional mechanisms are res