High temporal resolution breathheld 3D FIESTA CINE imaging: Validation of ventricular function in patients with chronic myocardial infarction
✍ Scribed by Dan W. Rettmann; Manojkumar Saranathan; Katherine C. Wu; Clerio F. Azevedo; David A. Bluemke; Thomas K.F. Foo
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 460 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1053-1807
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✦ Synopsis
Abstract
Purpose
To develop a gated single‐breathhold, high temporal resolution three‐dimensional (3D) CINE imaging technique and to evaluate its accuracy in volumetric and functional quantification in patients with chronic myocardial infarction.
Materials and Methods
A 3D CINE steady‐state free precession (SSFP) pulse sequence was developed incorporating variable temporal sampling of the low and high spatial frequency k‐space data to reduce breathhold time and parallel imaging to increase temporal resolution. Reconstruction with retrospective interpolation enabled complete R‐R interval coverage. Feasibility was assessed in eight patients with chronic myocardial infarction and ventricular functional values were compared to those of a 2D CINE acquisition.
Results
There was no significant difference between the 3D CINE and 2D CINE for end‐diastolic volume (168 ± 73 vs. 177 ± 59 mL, respectively; P < 0.27), end‐systolic volume (81 ± 62 vs. 79 ± 53 mL; P < 0.81), and ejection fraction (EF) measurements (55 ± 14% vs. 58 ± 14%; P < 0.14). The mean difference in EF was less than 2.5%. A wall motion assessment indicated a good agreement, with a weighted kappa value of 0.62.
Conclusion
High temporal resolution 3D CINE SSFP imaging of the whole heart can be obtained in a single breathhold and yield ventricular function measurements similar to 2D CINE methods. J. Magn. Reson. Imaging 2007;25:1141–1146. © 2007 Wiley‐Liss, Inc.