High-temperature Chlorination of Amines and Acylamines

✍ Scribed by Dr. H. Holtschmidt

• Book ID: 102724269
• Publisher: John Wiley and Sons
• Year: 1962
• Tongue: English
• Weight: 705 KB
• Volume: 1
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.196206321

✦ Synopsis

Abstract

High‐temperature chlorination of acyl derivatives of primary and secondary amines and of tertiary alkyl amines usually yields compounds containing either the imidochloride (monochloromethyleneamino) group or the dichloroisocyanide (dichloromethyleneamino) group . In many cases, yields in the range of 80 to 95% are obtaied. Several ring‐opening and ring‐closing reactions ocurring under the conditions of high‐temperature chlorination ae described.