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High-sensitivity capillary and microchip electrophoresis using electrokinetic supercharging

✍ Scribed by Mohamed Dawod; Doo Soo Chung

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
249 KB
Volume
34
Category
Article
ISSN
1615-9306

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✦ Synopsis

Abstract

Electrokinetic supercharging (EKS) is considered as one of the most powerful online preconcentration techniques in electrophoresis. It combines the efficient preconcentration power of field‐amplified sample injection and the exceptional selective nature of transient isotachophoresis. It has a wide range of applications to different types of analytes ranging from small ions to large proteins and DNA fragments. This comprehensive review β€” up to date β€” provides listing for all the works, developments, and advances in EKS. The review will pay particular attention to innovations, new methodologies for manipulation, challenges for improving the detection sensitivity, and various applications of EKS in capillaries and microchips.

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