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High-Sensitivity Blood-Based Detection of Breast Cancer by Multi Photon Detection Diagnostic Proteomics

✍ Scribed by Drukier, Andrzej K.; Ossetrova, Nathasha; Schors, Elena; Krasik, Galya; Grigoriev, Ivan; Koenig, Christina; Sulkowski, Miko; Holcman, Jerzy; Brown, Larry R.; Tomaszewski, John E.; Schnall, Mitchell D.; Sainsbury, Richard; Lokshin, Anne E.; Godovac-Zimmermann, Jasminka

Book ID: 126211553
Publisher: American Chemical Society
Year: 2006
Tongue: English
Weight: 340 KB
Volume: 5
Category: Article
ISSN: 1535-3893
DOI: 10.1021/pr0600834

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Immunocytochemical detection (ICC) of isolated tumor cells in bone marrow (BM) is currently the most established method for monitoring early dissemination in epithelial cancer. However, the low sample size that can practically be analyzed restricts the sensitivity and reliability of the ICC method.