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High-sensitive fluorescent DNA sequencing and its application for detection and mass-screening of point mutations

✍ Scribed by Dr. Masahira Hattori; Katsuji Yoshioka; Yoshiyuki Sakaki


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
763 KB
Volume
13
Category
Article
ISSN
0173-0835

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## Abstract The present study reports a proof‐of‐principle for a sensitive genotyping assay approach that can detect single nucleotide polymorphisms (SNPs) based on fluorescence anisotropy measurements through a core–shell fluorescent nanoparticles assembly and ligase reaction. By incorporating the