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High-sensitive electrochemical detection of point mutation based on polymerization-induced enzymatic amplification

✍ Scribed by Kejun Feng; Jingjin Zhao; Zai-Sheng Wu; Jianhui Jiang; Guoli Shen; Ruqin Yu


Book ID
108072390
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
512 KB
Volume
26
Category
Article
ISSN
0956-5663

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Highly sensitive DNA detection and point
✍ Zai-Sheng Wu; Jian-Hui Jiang; Guo-Li Shen; Ru-Qin Yu πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 279 KB

A novel strategy is described for highly sensitive DNA detection and point mutation identification based on the combination of reverse molecular beacon with DNA ligase. A 5'-phosphoryl and 3'-ferrocene terminated DNA sequence is used as detection probe, which may be ligated to capture DNA immobilize