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High-risk human papilloma virus types and squamous cell carcinoma in patients with respiratory papillomas

✍ Scribed by Charles E. Moore; Brian J. Wiatrak; Kenneth D. McClatchey; Charles F. Koopmann; Thomas Giovanna R.; Carol R. Bradford; Thomas E. Carey

Book ID: 117400918
Publisher: SAGE Publications
Year: 1995
Tongue: English
Weight: 225 KB
Volume: 113
Category: Article
ISSN: 0194-5998
DOI: 10.1016/s0194-5998(05)80673-4

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## Abstract Human papillomavirus (HPV) infects the squamous epithelial cells of oral cavity and cervix leading to formation of warts that develops into the cancer. Human papillomavirus (HPV)‐16 and 18 encode E6 oncoprotein, which binds to and induces degradation of the tumour suppressor protein p53